Analisis Fitokimia Daun Kersen (Mutingia calabura) Sebagai Senyawa Bioaktif Potensial untuk Pengembangan Obat Herbal

Authors

  • Nursyifa Tiara Dwiputri Program Studi Biologi, Universitas Islam Negeri Sunan Gunung Djati, Bandung, Indonesia Author
  • Salsa Sabila Program Studi Biologi, Universitas Islam Negeri Sunan Gunung Djati, Bandung, Indonesia Author
  • Muhimatul Umami Program Studi Biologi, Universitas Islam Negeri Sunan Gunung Djati, Bandung, Indonesia Author

DOI:

https://doi.org/10.62588/otusedu.2025.v3i2.0266

Keywords:

Cherry leaves, flavonoids alkaloids, tannins, bioactive compounds

Abstract

This study aims to analyze the content of bioactive compounds in cherry leaf extract (Muntingia calabura L.) through qualitative phytochemical tests. Cherry leaves are known to have pharmacological potential such as antioxidants, antimicrobials, and anti-inflammatories, which come from their secondary metabolites. The extraction process was carried out by the maceration method using 96% ethanol as a solvent, followed by testing using specific reagents such as Mayer, Dragendorff, Wagner, FeCl₃, and foam tests. The results showed that cherry leaf extract contains flavonoids, alkaloids and tannins which are characterized by the formation of deposits and color changes in specific reagents, while the test for saponins showed negative results. The presence of alkaloids, flavonoids, and tannins supports the therapeutic potential of cherry leaves, so it is worthy of further research for the development of herbal medicine.

References

Amiruddin, Z. Z. (2007). Free radical scavenging activity of some plants available in Malaysia. International Journal of Pharmacy and Technology, 6, 87–91.

Ayed, A., Ennouri, M., & Attia, H. (2020). Effect of solvent evaporation method on phenolic compounds and the antioxidant activity of Moringa oleifera cultivated in Southern Tunisia. South African Journal of Botany, 129, 181–190.

Chaudhari, R. N., Jain, A. K., & Chatap, V. K. (2020). Phytochemical Screening, Antioxidant and Antimicrobial Potential of Leaves Extract of Muntingia calabura. Journal of Advanced Scientific Research, 11(4), 218–224.

Fitriyani, A., Lina, W., Siti, M., & Nuri. (2011). Antiinflamasi ekstrak metanol daun sirih merah (Piper crocatum Ruiz & Pav) pada tikus putih. Majalah Obat Tradisional, 16(1), 34–42.

Hamdayani, L. A., Fitriyanti, J. S., & Utami, Y. P. (2024). Total Flavonoid Levels and Antioxidant Activity of Kersen Leaf Extract (Muntingia calabura L.). Jurnal Katalisator, 9(1), 214–225.

Harborne, J. B. (1996). Metode fitokimia: Penuntun cara modern menganalisis tumbuhan (Cet. ke-2, K. Padmawinata & I. Soediro, Penerj.). Bandung: Penerbit ITB.

Ibrahim, I. A. A., Abdulla, M. A., Abdelwahab, S. I., Al-Bayaty, F., & Majid, N. A. (2012). Leaves extract of Muntingia calabura protects against gastric ulcer induced by ethanol in Sprague-Dawley rats. Clinical and Experimental Pharmacology, USA.

Khan, M. A., Najeeb, U., Hussain, S., Naeem, M., & Ahmad, A. (2018). Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Journal of Food and Drug Analysis, 26(1), 327–339.

Krishnan, A. (2009). Phytopharmacological study on Antidesma acidium Retz. – A folk plant [Disertasi, Rajiv Gandhi University of Health Sciences].

Kulikova, N. E., Chernobrovina, A. G., Roeva, N. N., & Popova, O. Yu. (2023). Evaporation as a method for obtaining plant concentrates. Food Processing: Techniques and Technology, 53(2), 335–346.

Mahmood, N. D., Nasir, N. L. M., Rofiee, M. S., Tohid, S. F. M., Ching, S. M., Teh, L. K., Salleh, M. Z., & Zakaria, Z. A. (2014). Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations. Pharmaceutical Biology, 52(12), 1598–1623.

Rusdi. (1990). Tetumbuhan sebagai sumber bahan obat. Padang: Pusat Penelitian Universitas Andalas.

Sangi, M. M. R. J., Runtuwene, H. E. I., Simbala, & Makang, V. M. A. (2008). Analisa fitokimia tumbuhan obat di Minahasa Utara. Chemistry Progress, 1(1), 47.

Satyajit. (2007). Kimia untuk farmasi: Bahan kimia organik, alam dan umum. Yogyakarta: Pustaka Pelajar.

Simamora, A., Santoso, A. W., Rahayu, I., & Timotius, K. H. (2020). Enzyme Inhibitory, Antioxidant, and Antibacterial Activities of Ethanol Fruit Extract of Muntingia calabura Linn. Journal of Herbmed Pharmacology, 9(4), 346–354.

Sowjanya, M., Srinivasulu, L., Lakshmi, B. K. M., Venkatrayulu, C., & Sainath, S. B. (2023). Phytochemical Analysis and Antimicrobial Activity of Muntingia calabura. Journal of Chemical Health Risks, 13(4), 247–255.

Zakaria, Z. A., Nor Hazalin, A. M. N., Zaid, S. N. H. M., Ghani, M. A., Hassan, M. H., Gopalan, H. K., & Sulaiman, M. R. (2007). Antinociceptive, anti-inflammatory and antipyretic effects of Muntingia calabura aqueous extract in animal models. Journal of Natural Medicines, 61(4), 443–448.

Downloads

Published

05-08-2025

How to Cite

Dwiputri, N. T. ., Sabila, S., & Umami, M. (2025). Analisis Fitokimia Daun Kersen (Mutingia calabura) Sebagai Senyawa Bioaktif Potensial untuk Pengembangan Obat Herbal. Otus Education: Jurnal Biologi Dan Pendidikan Biologi, 3(2), 51-58. https://doi.org/10.62588/otusedu.2025.v3i2.0266

Most read articles by the same author(s)

<< < 1 2 3 > >>